Our Research Defines Us

The goal of BBI’s tools and platforms is to enable our members to explore new opportunities at the interface of basic science and precision medicine.

Below are some recent examples of our work.

UW Medicine Fred Hutch Seattle Children's Hospital

News (1)

Sea Hub

SeaBridge

Lead Researchers

Jay Shendure

Marion Pepper

Cole Trapnell

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Sea Hub

The Brotman Baty Institute & The Seattle Hub for Synthetic Biology

Lead Researchers

Jay Shendure, Cole Trapnell, Marion Pepper, Sud Pinglay, Nobuhiko (Nobu) Hamazaki
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Mutational Scanning

Variant Effects Program

Lead Researchers

Lea Starita, Doug Fowler, Jay Shendure, Andrew Stergachis
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Genomics

BBI Advanced Technology Lab

Lead Researchers

Lea Starita

Jay Shendure

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Welcome to The Brotman Baty Institute

Welcome to The Brotman Baty Institute, an innovation hub for genomic research and precision medicine.

The BBI is a collaboration among Seattle’s three top research institutions—The University of Washington, Seattle Children’s Hospital, and Fred Hutchinson Cancer Research Center.

The offices of the Brotman Baty Institute and the UW Campus overlook Seattle’s Montlake Cut, Lake Union, and the city skyline. Photo courtesy of University of Washington Communications.

The offices of the Brotman Baty Institute and the UW Campus overlook Seattle’s Montlake Cut, Lake Union, and the city skyline. Photo courtesy of University of Washington Communications.

Our Resources

Investigators based at partner institutions have equal access to our platforms at identical costs.

Tools & Data

BBI tools and data support BBI members and researchers worldwide.

BBI provides data and a repository for our datasets, analysis code, and protocols. We also provide tutorials to assist you in downloading, analyzing, and exploring these datasets.

See Tools

Platforms

BBI Platforms support our research.

Our goal is to support the work of our faculty, researchers, and investigators by fostering collaboration and innovation.

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BBI Grant Program

The BBI invests in promising pilot research.

The Brotman Baty Institute (BBI) aims to create a community of investigators across the three founding institutions (UW, Fred Hutch, Seattle Children’s) to advance basic science and translational research with clear relevance to precision medicine. The BBI invests in innovative, collaborative projects that address basic science or translational research questions related to precision medicine. To learn more about the grants offered by BBI and to apply, contact info@brotmanbaty.org.

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Sep

16

2025

Events

Foege Hall South 060: 3720 15th Ave NE, Seattle, WA 98105

2025 Long-Read Sequencing Symposium

Sep 16, 2025 | 10:30AM - 4:30PM

Connecting Researchers Locally

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Collaborators

BBI members include more than 300 faculty at The University of Washington, Seattle Children’s Hospital, and Fred Hutchinson Cancer Research Center.
Learn about membership at BBI

Our Commitment to Diversity, Equity, and Inclusion

BBI embraces diversity and inclusion in all its work and, like the University of Washington, believes diversity is integral to excellence.

We value and honor diverse experiences and perspectives, strive to create welcoming and respectful learning environments, and promote access, opportunity, and justice for all.

News

Promising Young Scientist: Curran Oi Demonstrates ‘Creativity and Courage’ as a Post-doc in Genome Sciences

June 26, 2025 | by BBI Communications

‘Hardest part is just sticking with it and being adaptable’

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Science-Art Encounter Enables Artists to ‘Experience Scientific Spaces Otherwise Inaccessible’

June 24, 2025 | by BBI Communications

‘I see science as physical craftsmanship… it’s a finely choreographed motion’

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From Data to Diagnosis: BBI Survey Reveals Roadblocks and Opportunities for Using Functional Evidence in Variant Classification

June 17, 2025 | by BBI Communications

New survey among genetics professionals indicates a strong demand for a comprehensive database with standardized metrics to support using functional evidence in clinical variant interpretation

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